What the FDA labels say about taking them together
Avibactam/ceftazidime and metronidazole
Avibactam/ceftazidime's FDA label of April 30, 2025 names metronidazole in its warnings and precautions section; the metronidazole labels PlainMeds reads (4) do not name avibactam/ceftazidime.
Check it at the source: the avibactam/ceftazidime FDA label on DailyMed (effective April 30, 2025, Allergan, Inc.); the metronidazole FDA label on DailyMed (effective September 3, 2024, Aurobindo Pharma Limited).
What does the avibactam/ceftazidime label say about metronidazole?
Avibactam/ceftazidime label, warnings and precautionsThe reduction in clinical cure rates was more marked in patients treated with AVYCAZ plus metronidazole compared to meropenem-treated patients.
Source: FDA drug label (AVYCAZ), NDA206494 (Abbvie), as published by Allergan, Inc., effective April 30, 2025 (SPL set d9c2803f-dc9c-4b19-b4a3-8303bc8c15fd), via openFDA; the full label on DailyMed
What does the metronidazole label say about avibactam/ceftazidime?
Metronidazole's label (effective September 3, 2024) and its 3 other brand-application labels do not name avibactam/ceftazidime in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Metronidazole), Aurobindo Pharma Limited, effective September 3, 2024 (SPL set f68397ee-67db-472e-8607-4300064e37df), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Avibactam/ceftazidime | Metronidazole | |
|---|---|---|
| Labeled for | Urinary tract infections | Bacterial infections |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | $0.102 per tablet 250 mg tablet |
| Shortage now | No current entry | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once