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What the FDA labels say about taking them together

Cefixime and warfarin

Cefixime's FDA label of August 5, 2026 names warfarin in its drug interactions section; the warfarin label PlainMeds reads does not name cefixime. The cefixime label: “… bleeding, has been reported when cefixime is administered concomitantly with warfarin and anticoagulants.”

Check it at the source: the cefixime FDA label on DailyMed (effective August 5, 2026, REMEDYREPACK INC.); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).

What does the cefixime label say about warfarin?

Cefixime label, drug interactions

DRUG INTERACTIONS Elevated carbamazepine levels have been reported in postmarketing experience when cefixime is administered concomitantly. ( 7.1 ) Increased prothrombin time, with or without clinical bleeding, has been reported when cefixime is administered concomitantly with warfarin and anticoagulants.

Source: FDA drug label (CEFIXIME), NDA203195 (Lupin Ltd), as published by REMEDYREPACK INC., effective August 5, 2026 (SPL set 3194433c-c04e-442b-9668-fbeb0a15bac7), via openFDA; the full label on DailyMed

What does the warfarin label say about cefixime?

Warfarin's label (effective May 29, 2026) does not name cefixime in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

6Cefixime generic labelers
19Warfarin generic labelers
CefiximeWarfarin
Labeled forBacterial infections, Urinary tract infectionsBlood clots (DVT and PE), Atrial fibrillation
Boxed warningNoYes
Pharmacy cost (NADAC)$10.03 per capsule 400 mg capsule$0.093 per tablet 2 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?