What the FDA labels say about taking them together
Cefepime and furosemide
Cefepime's FDA label of November 15, 2021 names furosemide in its drug interactions section; the furosemide labels PlainMeds reads (4) do not name cefepime. The cefepime label: “Nephrotoxicity has been reported with concomitant administration of cephalosporins with potent diuretics such as furosemide. Monitor renal function.”
Check it at the source: the cefepime FDA label on DailyMed (effective November 15, 2021, Qilu Pharmaceutical Co., Ltd.); the furosemide FDA label on DailyMed (effective September 30, 2025, Validus Pharmaceuticals LLC).
What does the cefepime label say about furosemide?
Cefepime label, drug interactionsDiuretics: nephrotoxicity has been reported following concomitant administration of other cephalosporins with potent diuretics such as furosemide. Monitor renal function.
Source: FDA drug label (Cefepime Hydrochloride And Dextrose, NDA050821), B. Braun Medical Inc., effective April 7, 2026 (SPL set 57517a0e-ec1b-4605-a7cc-7e3801158ec9), via openFDA
Source: FDA drug label (Cefepime, NDA050817), Baxter Healthcare Corporation, effective June 25, 2026 (SPL set be5f8ca6-7232-423a-a2d5-cccb7abe7921), via openFDA
Source: FDA drug label (Cefepime), Qilu Pharmaceutical Co., Ltd., effective November 15, 2021 (SPL set 80b4c811-4a71-47fb-8565-85ce9d0f782c), via openFDA; the full label on DailyMed
What does the furosemide label say about cefepime?
Furosemide's label (effective September 30, 2025) and its 3 other brand-application labels do not name cefepime in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Lasix), Validus Pharmaceuticals LLC, effective September 30, 2025 (SPL set 2c9b4d8f-0770-482d-a9e6-9c616a440b1a), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cefepime | Furosemide | |
|---|---|---|
| Labeled for | Urinary tract infections | Heart failure, High blood pressure, Edema (fluid retention) |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.490 per mL 20 mg/2 mL vial |
| Shortage now | A presentation being discontinued | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once