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What the FDA labels say about taking them together

Carbidopa/levodopa and linezolid

Carbidopa/levodopa's FDA label (Dhivy) of August 21, 2026 names linezolid in its contraindications section; the linezolid labels PlainMeds reads (3) do not name carbidopa/levodopa. The carbidopa/levodopa label: “CONTRAINDICATIONS DHIVY is contraindicated in patients Currently taking a nonselective monoamine oxidase (MAO) inhibitor or have recently (within 2 weeks) taken a nonselective MAO inhibitor.”

Check it at the source: the carbidopa/levodopa FDA label on DailyMed (effective August 1, 2026, Organon LLC); the linezolid FDA label on DailyMed (effective June 19, 2026, Hospira, Inc.).

What does the carbidopa/levodopa label say about linezolid?

Dhivy label (Avion Pharmaceuticals, LLC, August 21, 2026), contraindications

CONTRAINDICATIONS DHIVY is contraindicated in patients Currently taking a nonselective monoamine oxidase (MAO) inhibitor (e.g., phenelzine, linezolid, and tranylcypromine) or have recently (within 2 weeks) taken a nonselective MAO inhibitor.

Source: FDA drug label (Dhivy, NDA214869), Avion Pharmaceuticals, LLC, effective August 21, 2026 (SPL set 39d79ade-8ee0-40ba-9fdd-13045b8ddbdf), via openFDA

Source: FDA drug label (SINEMET), Organon LLC, effective August 1, 2026 (SPL set 9b17b028-964a-473c-823d-81423535bd66), via openFDA; the full label on DailyMed

What does the linezolid label say about carbidopa/levodopa?

Linezolid's label (effective June 19, 2026) and its 2 other brand-application labels do not name carbidopa/levodopa in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Linezolid), Hospira, Inc., effective June 19, 2026 (SPL set c401f1a8-cc37-461b-bfef-f2e156629bf8), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

33Carbidopa/levodopa generic labelers
24Linezolid generic labelers
Carbidopa/levodopaLinezolid
Labeled forParkinson's diseaseBacterial infections
Boxed warningNoNo
Pharmacy cost (NADAC)$0.0759 per tablet 25-100 tablet$1.44 per tablet 600 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?