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What the FDA labels say about taking them together

Carbamazepine and paclitaxel

Paclitaxel's FDA label of January 21, 2026 names carbamazepine in its drug interactions section; the carbamazepine labels PlainMeds reads (3) do not name paclitaxel.

Check it at the source: the carbamazepine FDA label on DailyMed (effective August 20, 2026, Novartis Pharmaceuticals Corporation); the paclitaxel FDA label on DailyMed (effective January 21, 2026, Natco Pharma USA LLC).

What does the carbamazepine label say about paclitaxel?

Carbamazepine's label (effective August 20, 2026) and its 2 other brand-application labels do not name paclitaxel in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Tegretol), Novartis Pharmaceuticals Corporation, effective August 20, 2026 (SPL set 8d409411-aa9f-4f3a-a52c-fbcb0c3ec053), via openFDA; the full label on DailyMed

What does the paclitaxel label say about carbamazepine?

Paclitaxel label, drug interactions

Caution should be exercised when paclitaxel is concomitantly administered with known substrates (eg, midazolam, buspirone, felodipine, lovastatin, eletriptan, sildenafil, simvastatin, and triazolam), inhibitors (eg, atazanavir, clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir, saquinavir, and telithromycin), and inducers (eg, rifampin and carbamazepine) of CYP3A4. ( See CLINICAL PHARMACOLOGY section. ) Caution should also be exercised when paclitaxel is concomitantly administered with known substrates (eg, repaglinide and rosiglitazone), inhibitors (eg, gemfibrozil), and inducers (eg, rifampin) of CYP2C8. ( See CLINICAL PHARMACOLOGY. …

Source: FDA drug label (Paclitaxel), Natco Pharma USA LLC, effective January 21, 2026 (SPL set a1eb16b4-285b-4e81-9c4e-1244d4a52af8), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

42Carbamazepine generic labelers
19Paclitaxel generic labelers
CarbamazepinePaclitaxel
Labeled forBipolar disorder, Seizures and epilepsyBreast cancer, Lung cancer
Boxed warningYesYes
Pharmacy cost (NADAC)$0.119 per tablet 200 mg tabletn/a
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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