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What the FDA labels say about taking them together

Carbamazepine and mifepristone

Mifepristone's FDA label of September 25, 2025 names carbamazepine in its drug interactions section; the carbamazepine labels PlainMeds reads (3) do not name mifepristone. The mifepristone label: “Avoid co-administration of mifepristone and CYP3A inducers such as rifampin, rifabutin, rifapentin, phenobarbital, phenytoin, carbamazepine, and St. John's wort.”

Check it at the source: the carbamazepine FDA label on DailyMed (effective August 20, 2026, Novartis Pharmaceuticals Corporation); the mifepristone FDA label on DailyMed (effective September 25, 2025, Corcept Therapeutics Incorporated).

What does the carbamazepine label say about mifepristone?

Carbamazepine's label (effective August 20, 2026) and its 2 other brand-application labels do not name mifepristone in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Tegretol), Novartis Pharmaceuticals Corporation, effective August 20, 2026 (SPL set 8d409411-aa9f-4f3a-a52c-fbcb0c3ec053), via openFDA; the full label on DailyMed

What does the mifepristone label say about carbamazepine?

Mifepristone label, drug interactions

Avoid co-administration of mifepristone and CYP3A inducers such as rifampin, rifabutin, rifapentin, phenobarbital, phenytoin, carbamazepine, and St. John's wort.

Source: FDA drug label (Mifepristone), Corcept Therapeutics Incorporated, effective September 25, 2025 (SPL set 63c068cd-9370-460f-829b-70e8c7ebe91e), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

42Carbamazepine generic labelers
3Mifepristone generic labelers
CarbamazepineMifepristone
Labeled forBipolar disorder, Seizures and epilepsyn/a
Boxed warningYesYes
Pharmacy cost (NADAC)$0.119 per tablet 200 mg tabletn/a
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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