What the FDA labels say about taking them together
Carbamazepine and ganaxolone
Ganaxolone's FDA label of November 28, 2025 names carbamazepine in its drug interactions section; the carbamazepine labels PlainMeds reads (3) do not name ganaxolone. The ganaxolone label: “In patients on a stable ZTALMY dosage who are initiating or increasing the dosages of enzyme-inducing antiepileptic drugs, the ZTALMY dosage may need to be increased; …”
Check it at the source: the carbamazepine FDA label on DailyMed (effective August 20, 2026, Novartis Pharmaceuticals Corporation); the ganaxolone FDA label on DailyMed (effective November 28, 2025, Immedica Pharma US Inc).
What does the carbamazepine label say about ganaxolone?
Carbamazepine's label (effective August 20, 2026) and its 2 other brand-application labels do not name ganaxolone in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Tegretol), Novartis Pharmaceuticals Corporation, effective August 20, 2026 (SPL set 8d409411-aa9f-4f3a-a52c-fbcb0c3ec053), via openFDA; the full label on DailyMed
What does the ganaxolone label say about carbamazepine?
Ganaxolone label, drug interactionsIn patients on a stable ZTALMY dosage who are initiating or increasing the dosages of enzyme-inducing antiepileptic drugs (e.g., carbamazepine, phenytoin, phenobarbital, and primidone), the ZTALMY dosage may need to be increased; however, do not exceed the maximum daily dosage of ZTALMY [see Dosage and Administration (2.1) ].
Source: FDA drug label (ZTALMY), Immedica Pharma US Inc, effective November 28, 2025 (SPL set d91612c4-b03a-4be4-a1ee-6a13e3b83d4e), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Carbamazepine | Ganaxolone | |
|---|---|---|
| Labeled for | Bipolar disorder, Seizures and epilepsy | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.119 per tablet 200 mg tablet | n/a |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once