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What the FDA labels say about taking them together

Carbamazepine and elbasvir/grazoprevir

Elbasvir/grazoprevir's FDA label of March 13, 2026 names carbamazepine in its contraindications section; the carbamazepine labels PlainMeds reads (3) do not name elbasvir/grazoprevir.

Check it at the source: the carbamazepine FDA label on DailyMed (effective August 20, 2026, Novartis Pharmaceuticals Corporation); the elbasvir/grazoprevir FDA label on DailyMed (effective March 13, 2026, Merck Sharp & Dohme LLC).

What does the carbamazepine label say about elbasvir/grazoprevir?

Carbamazepine's label (effective August 20, 2026) and its 2 other brand-application labels do not name elbasvir/grazoprevir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Tegretol), Novartis Pharmaceuticals Corporation, effective August 20, 2026 (SPL set 8d409411-aa9f-4f3a-a52c-fbcb0c3ec053), via openFDA; the full label on DailyMed

What does the elbasvir/grazoprevir label say about carbamazepine?

Elbasvir/grazoprevir label, contraindications

Named in a table that the FDA label file prints without its column breaks; the full label shows the table.

Source: FDA drug label (ZEPATIER), Merck Sharp & Dohme LLC, effective March 13, 2026 (SPL set 164dc02a-9180-426a-b8b5-04ab39d2bbd4), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

42Carbamazepine generic labelers
0Elbasvir/grazoprevir generic labelers
CarbamazepineElbasvir/grazoprevir
Labeled forBipolar disorder, Seizures and epilepsyHepatitis C
Boxed warningYesYes
Pharmacy cost (NADAC)$0.119 per tablet 200 mg tabletn/a
Shortage nowA presentation being discontinuedA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?