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What the FDA labels say about taking them together

Carbamazepine and dabigatran

Carbamazepine's FDA label of August 20, 2026 names dabigatran in its drug interactions section; the dabigatran labels PlainMeds reads (2) do not name carbamazepine. The carbamazepine label: “Concomitant use of carbamazepine with rivaroxaban, apixaban, dabigatran, and edoxaban is expected to result in decreased plasma concentrations of these anticoagulants that may be insufficient to achieve the intended …”

Check it at the source: the carbamazepine FDA label on DailyMed (effective August 20, 2026, Novartis Pharmaceuticals Corporation); the dabigatran FDA label on DailyMed (effective June 25, 2025, Boehringer Ingelheim Pharmaceuticals Inc.).

What does the carbamazepine label say about dabigatran?

Carbamazepine label, drug interactions

Concomitant use of carbamazepine with rivaroxaban, apixaban, dabigatran, and edoxaban (direct acting oral anticoagulants) is expected to result in decreased plasma concentrations of these anticoagulants that may be insufficient to achieve the intended therapeutic effect.

Carbatrol label (Takeda Pharmaceuticals America, Inc., August 17, 2026), drug interactions

Acetaminophen, albendazole, alprazolam, aprepitant, buprenorphine, apixaban (6), bupropion, buspirone, citalopram, clobazam, clonazepam, clozapine, corticosteroids (e.g. prednisolone, dexamethasone), cyclosporin, dabigatran (6), delavirdine, desipramine, diazepam, dicumarol, dihydropyridine calcium channel blockers (e.g., felodipine), doxycycline, edoxaban (6), eslicarbazepine, ethosuximide, everolimus, felbamate, haloperidol, imatinib, itraconazole, lamotrigine, levothyroxine, lorazepam, methadone, methsuximide, midazolam, mirtazapine, nefazodone, nortriptyline, olanzapine, oral and other hormonal contraceptives (2), oxcarbazepine, paliperidone, phenytoin (3), praziquantel, protease …

Source: FDA drug label (Carbatrol, NDA020712), Takeda Pharmaceuticals America, Inc., effective August 17, 2026 (SPL set bc03e499-5bac-4293-bff4-6864153a624d), via openFDA

Source: FDA drug label (Tegretol), Novartis Pharmaceuticals Corporation, effective August 20, 2026 (SPL set 8d409411-aa9f-4f3a-a52c-fbcb0c3ec053), via openFDA; the full label on DailyMed

What does the dabigatran label say about carbamazepine?

Dabigatran's label (effective June 25, 2025) and its 1 other brand-application label do not name carbamazepine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Pradaxa), Boehringer Ingelheim Pharmaceuticals Inc., effective June 25, 2025 (SPL set ba74e3cd-b06f-4145-b284-5fd6b84ff3c9), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

42Carbamazepine generic labelers
16Dabigatran generic labelers
CarbamazepineDabigatran
Labeled forBipolar disorder, Seizures and epilepsyAtrial fibrillation, Blood clots (DVT and PE), Stroke prevention
Boxed warningYesYes
Pharmacy cost (NADAC)$0.119 per tablet 200 mg tablet$0.795 per capsule 150 mg capsule
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?