What the FDA labels say about taking them together
Brivaracetam and carbamazepine
Brivaracetam's FDA label of August 20, 2026 names carbamazepine in its drug interactions section, and carbamazepine's label names brivaracetam too. The brivaracetam label: “Because of increased exposure to carbamazepine metabolite, if tolerability issues arise, consider reducing carbamazepine dosage in patients on concomitant BRIVIACT.”
Check it at the source: the brivaracetam FDA label on DailyMed (effective August 20, 2026, UCB, Inc.); the carbamazepine FDA label on DailyMed (effective August 20, 2026, Novartis Pharmaceuticals Corporation).
What does the brivaracetam label say about carbamazepine?
Brivaracetam label, drug interactionsBecause of increased exposure to carbamazepine metabolite, if tolerability issues arise, consider reducing carbamazepine dosage in patients on concomitant BRIVIACT.
Source: FDA drug label (Briviact), NDA205836 (Ucb Inc), as published by UCB, Inc., effective August 20, 2026 (SPL set 3cf2f439-0e97-443e-8e33-25ecef616f6c), via openFDA; the full label on DailyMed
What does the carbamazepine label say about brivaracetam?
Carbamazepine label, drug interactionsAccordingly, the dosage of Tegretol should be adjusted and/or the plasma levels monitored when used concomitantly with loxapine, quetiapine, valproic acid, or brivaracetam.
Source: FDA drug label (Tegretol), Novartis Pharmaceuticals Corporation, effective August 20, 2026 (SPL set 8d409411-aa9f-4f3a-a52c-fbcb0c3ec053), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Brivaracetam | Carbamazepine | |
|---|---|---|
| Labeled for | Seizures and epilepsy | Bipolar disorder, Seizures and epilepsy |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.259 per tablet 100 mg tablet | $0.119 per tablet 200 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once