What the FDA labels say about taking them together
Calcium chloride, potassium chloride, sodium chloride and sodium lactate and pseudoephedrine
Calcium chloride, potassium chloride, sodium chloride and sodium lactate's FDA label (Lactated Ringers) of January 2, 2018 names pseudoephedrine in its drug interactions section; the pseudoephedrine label PlainMeds reads does not name calcium chloride, potassium chloride, sodium chloride and sodium lactate. The calcium chloride, potassium chloride, sodium chloride and sodium lactate label: “Renal clearance of alkaline drugs, such as sympathomimetics, dextroamphetamine (dexamphetamine) sulfate, and fenfluramine (phenfluramine) hydrochloride may be decreased.”
Check it at the source: the calcium chloride, potassium chloride, sodium chloride and sodium lactate FDA label on DailyMed (effective October 29, 2025, Baxter Healthcare Company); the pseudoephedrine FDA label on DailyMed (effective October 30, 2025, L. Perrigo Company).
What does the calcium chloride, potassium chloride, sodium chloride and sodium lactate label say about pseudoephedrine?
Lactated Ringers label (Baxter Healthcare Company, January 2, 2018), drug interactionsRenal clearance of alkaline drugs, such as sympathomimetics (e.g., ephedrine, pseudoephedrine), dextroamphetamine (dexamphetamine) sulfate, and fenfluramine (phenfluramine) hydrochloride may be decreased.
Source: FDA drug label (Lactated Ringers, NDA018921), Baxter Healthcare Company, effective January 2, 2018 (SPL set 5215ec33-8cfe-4885-ae92-e6a12100bd27), via openFDA
Source: FDA drug label (Lactated Ringers), Baxter Healthcare Company, effective October 29, 2025 (SPL set dad7735c-709b-40ea-ab7a-15577e24a966), via openFDA; the full label on DailyMed
What does the pseudoephedrine label say about calcium chloride, potassium chloride, sodium chloride and sodium lactate?
Pseudoephedrine's label (effective October 30, 2025) does not name calcium chloride, potassium chloride, sodium chloride and sodium lactate in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Good Sense Suphedrine 12 Hour), L. Perrigo Company, effective October 30, 2025 (SPL set 1de8a7f6-e7bb-437d-8794-c4b9f43b89c9), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Calcium chloride, potassium chloride, sodium chloride and sodium lactate | Pseudoephedrine | |
|---|---|---|
| Labeled for | n/a | Cough and cold |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0038 per mL Lactated ringers injection | $0.281 per tablet 120 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once