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What the FDA labels say about taking them together

Bupropion and triptorelin

Triptorelin's FDA label (Triptodur) of September 14, 2025 names bupropion in its warnings and precautions section; the bupropion labels PlainMeds reads (4) do not name triptorelin.

Check it at the source: the bupropion FDA label on DailyMed (effective June 21, 2024); the triptorelin FDA label on DailyMed (effective June 30, 2026, Verity Pharmaceuticals Inc.).

What does the bupropion label say about triptorelin?

Bupropion's label (effective June 21, 2024) and its 3 other brand-application labels do not name triptorelin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (BUPROPION HYDROCHLORIDE), Epic Pharma LLC, effective June 21, 2024 (SPL set 9fb44e96-6160-4a4a-90cb-91764c0dcd89), via openFDA; the full label on DailyMed

What does the triptorelin label say about bupropion?

Triptodur label (Azurity Pharmaceuticals, Inc., September 14, 2025), warnings and precautions

These included patients with a history of seizures, epilepsy, cerebrovascular disorders, central nervous system anomalies or tumors, and patients on concomitant medications that have been associated with convulsions such as bupropion and SSRIs.

Source: FDA drug label (Triptodur, NDA208956), Azurity Pharmaceuticals, Inc., effective September 14, 2025 (SPL set f41380e7-b830-432d-a5f5-a872932f107e), via openFDA

Source: FDA drug label (Trelstar), Verity Pharmaceuticals Inc., effective June 30, 2026 (SPL set b1b84d62-a369-a4b7-5c41-dd1f553a18f3), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

69Bupropion generic labelers
0Triptorelin generic labelers
BupropionTriptorelin
Labeled forDepression, Quitting smokingProstate cancer
Boxed warningYesNo
Pharmacy cost (NADAC)$0.0785 per tablet 150 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?