What the FDA labels say about taking them together
Bupropion and nafarelin
Nafarelin's FDA label of March 5, 2026 names bupropion in its warnings section; the bupropion labels PlainMeds reads (4) do not name nafarelin.
Check it at the source: the bupropion FDA label on DailyMed (effective June 21, 2024); the nafarelin FDA label on DailyMed (effective March 5, 2026, Pfizer Laboratories Div Pfizer Inc).
What does the bupropion label say about nafarelin?
Bupropion's label (effective June 21, 2024) and its 3 other brand-application labels do not name nafarelin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (BUPROPION HYDROCHLORIDE), Epic Pharma LLC, effective June 21, 2024 (SPL set 9fb44e96-6160-4a4a-90cb-91764c0dcd89), via openFDA; the full label on DailyMed
What does the nafarelin label say about bupropion?
Nafarelin label, warningsThese have included patients with a history of seizures, epilepsy, cerebrovascular disorders, central nervous system anomalies or tumors, and patients on concomitant medications that have been associated with convulsions such as bupropion and SSRIs.
Source: FDA drug label (Synarel), Pfizer Laboratories Div Pfizer Inc, effective March 5, 2026 (SPL set d0aa57cb-d2f4-46d7-af43-7c8b06aa81a6), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Bupropion | Nafarelin | |
|---|---|---|
| Labeled for | Depression, Quitting smoking | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.0785 per tablet 150 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once