Buprenorphine · larger labeled portfolio than Codeine
SPL labels Buprenorphine + Codeine as minor; Buprenorphine 28 / Codeine 27 in that band.
Mechanism on file: Both of these drugs slow down the central nervous system and breathing. Taking them together increases the risk of dangerous side effects like very slow breathing or low blood pressure.
FDA SPL severity: Minor
Buprenorphine + Codeine · SPL mechanism field
Both of these drugs slow down the central nervous system and breathing. Taking them together increases the risk of dangerous side effects like very slow breathing or low blood pressure.
Minor band excerpt · Buprenorphine with Codeine
If urgent use of an opioid is necessary, use test doses and frequent titration of small doses of other opioids (such as oxycodone, hydrocodone, oxymorphone, hydrocodone, or buprenorphine) to treat pain while closely monitoring blood pressure and signs and symptoms of CNS and respiratory depression.
Buprenorphine · 29 SPL pairs (broader portfolio than Codeine)
- Alprazolam minor
- Buprenorphine (Pain) minor
- Buprenorphine/Naloxone minor
- Carbamazepine minor
Codeine · 27 minor + 27 total pairs
- Acetaminophen minor
- Alprazolam minor
- Bupropion minor
- Butorphanol minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.