What the FDA labels say about taking them together
Brodalumab and warfarin
Brodalumab's FDA label of May 28, 2026 names warfarin in its drug interactions section; the warfarin label PlainMeds reads does not name brodalumab. The brodalumab label: “… with a narrow therapeutic index, consider monitoring for effect (e.g., for warfarin) or drug concentration (e.g., for cyclosporine) and consider dosage modification of the CYP450 substrate.”
Check it at the source: the brodalumab FDA label on DailyMed (effective May 28, 2026, Bausch Health US LLC); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).
What does the brodalumab label say about warfarin?
Brodalumab label, drug interactionsTherefore, upon initiation or discontinuation of SILIQ in patients who are receiving concomitant drugs which are CYP450 substrates, particularly those with a narrow therapeutic index, consider monitoring for effect (e.g., for warfarin) or drug concentration (e.g., for cyclosporine) and consider dosage modification of the CYP450 substrate [see Clinical Pharmacology ( 12.3 )].
Source: FDA drug label (Siliq), BLA761032 (Valeant Luxembourg), as published by Bausch Health US LLC, effective May 28, 2026 (SPL set 1a550c33-456a-4833-814e-8591aea7c688), via openFDA; the full label on DailyMed
What does the warfarin label say about brodalumab?
Warfarin's label (effective May 29, 2026) does not name brodalumab in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Brodalumab | Warfarin | |
|---|---|---|
| Labeled for | Psoriasis | Blood clots (DVT and PE), Atrial fibrillation |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | n/a | $0.093 per tablet 2 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once