What the FDA labels say about taking them together
Betaxolol and verapamil
Betaxolol's FDA label of December 20, 2023 names verapamil in its drug interactions section; verapamil's label does not name betaxolol itself but warns about its class (Beta blockers). The betaxolol label: “… disturbances, including complete heart block, were more likely to occur with either verapamil or diltiazem.”
Check it at the source: the betaxolol FDA label on DailyMed (effective December 20, 2023, Epic Pharma LLC); the verapamil FDA label on DailyMed (effective April 6, 2026, Zydus Pharmaceuticals (USA) Inc.).
What does the betaxolol label say about verapamil?
Betaxolol label, drug interactionsHypotension was more likely to occur if the calcium antagonist were a dihydropyridine derivative, eg, nifedipine, while left ventricular failure and AV conduction disturbances, including complete heart block, were more likely to occur with either verapamil or diltiazem.
Source: FDA drug label (Betaxolol), Epic Pharma LLC, effective December 20, 2023 (SPL set bf716efe-0a9f-43b1-9d8a-c69330b82e18), via openFDA; the full label on DailyMed
What does the verapamil label say about betaxolol?
Verapamil's label does not name betaxolol itself; it warns about its class (Beta blockers):
Verapamil label, drug interactionsAsymptomatic bradycardia (36 beats/min) with a wandering atrial pacemaker has been observed in a patient receiving concomitant timolol (a beta-adrenergic blocker) eyedrops and oral verapamil.
Verapamil label, drug interactionsVerapamil administered concomitantly with oral antihypertensive agents (e.g., vasodilators, angiotensin-converting enzyme inhibitors, diuretics, beta-blockers) will usually have an additive effect on lowering blood pressure.
Source: FDA drug label (Verapamil hydrochloride), Zydus Pharmaceuticals (USA) Inc., effective April 6, 2026 (SPL set e19ab8d8-dae5-489d-9805-7e7407bea06d), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Betaxolol | Verapamil | |
|---|---|---|
| Labeled for | High blood pressure, Glaucoma | High blood pressure, Atrial fibrillation, Angina |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.591 per tablet 10 mg tablet | $0.191 per tablet 180 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once