What the FDA labels say about taking them together
Baricitinib and probenecid
Baricitinib's FDA label of June 30, 2026 names probenecid in its drug interactions section; the probenecid label PlainMeds reads does not name baricitinib. The baricitinib label: “DRUG INTERACTIONS In patients taking strong Organic Anion Transporter 3 (OAT3) inhibitors (e.g., probenecid) the recommended dosage should be reduced.”
Check it at the source: the baricitinib FDA label on DailyMed (effective June 30, 2026, Eli Lilly and Company); the probenecid FDA label on DailyMed (effective January 5, 2021, Lannett Company, Inc.).
What does the baricitinib label say about probenecid?
Baricitinib label, drug interactionsDRUG INTERACTIONS In patients taking strong Organic Anion Transporter 3 (OAT3) inhibitors (e.g., probenecid) the recommended dosage should be reduced.
Source: FDA drug label (Olumiant), Eli Lilly and Company, effective June 30, 2026 (SPL set 866e9f35-9035-4581-a4b1-75a621ab55cf), via openFDA; the full label on DailyMed
What does the probenecid label say about baricitinib?
Probenecid's label (effective January 5, 2021) does not name baricitinib in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Probenecid), Lannett Company, Inc., effective January 5, 2021 (SPL set ab497fd8-00c3-4364-b003-b39d21fbdf38), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Baricitinib | Probenecid | |
|---|---|---|
| Labeled for | Rheumatoid arthritis, COVID-19 | Gout |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $92.54 per tablet 2 mg tablet | $0.636 per tablet 500 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once