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What the FDA labels say about taking them together

Azathioprine and warfarin

Azathioprine's FDA label of November 8, 2025 names warfarin in its drug interactions section; the warfarin label PlainMeds reads does not name azathioprine.

Check it at the source: the azathioprine FDA label on DailyMed (effective November 8, 2025, Sebela Pharmaceuticals Inc.); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).

What does the azathioprine label say about warfarin?

Azathioprine label, drug interactions

Use with Warfarin: IMURAN may inhibit the anticoagulant effect of warfarin.

Source: FDA drug label (IMURAN), NDA016324 (Legacy), as published by Sebela Pharmaceuticals Inc., effective November 8, 2025 (SPL set 606101a0-6244-7eff-e053-2a91aa0acadd), via openFDA; the full label on DailyMed

What does the warfarin label say about azathioprine?

Warfarin's label (effective May 29, 2026) does not name azathioprine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

17Azathioprine generic labelers
19Warfarin generic labelers
AzathioprineWarfarin
Labeled forOrgan transplant rejection, Rheumatoid arthritisBlood clots (DVT and PE), Atrial fibrillation
Boxed warningYesYes
Pharmacy cost (NADAC)$0.124 per tablet 50 mg tablet$0.093 per tablet 2 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?