What the FDA labels say about taking them together
Avibactam/aztreonam and probenecid
Avibactam/aztreonam's FDA label of June 24, 2026 names probenecid in its drug interactions section; the probenecid label PlainMeds reads does not name avibactam/aztreonam. The avibactam/aztreonam label: “DRUG INTERACTIONS 7.1 OAT 1 and 3 Transport Inhibitors Concomitant use of organic anion transporter (OAT) 1 and OAT 3 transporter inhibitors (e.g., probenecid) with EMBLAVEO is not recommended.”
Check it at the source: the avibactam/aztreonam FDA label on DailyMed (effective June 24, 2026, AbbVie Inc.); the probenecid FDA label on DailyMed (effective January 5, 2021, Lannett Company, Inc.).
What does the avibactam/aztreonam label say about probenecid?
Avibactam/aztreonam label, drug interactionsDRUG INTERACTIONS 7.1 OAT 1 and 3 Transport Inhibitors Concomitant use of organic anion transporter (OAT) 1 and OAT 3 transporter inhibitors (e.g., probenecid) with EMBLAVEO is not recommended.
Source: FDA drug label (EMBLAVEO), AbbVie Inc., effective June 24, 2026 (SPL set be1a6c99-d4b3-46d7-9e99-6e5f9fab556a), via openFDA; the full label on DailyMed
What does the probenecid label say about avibactam/aztreonam?
Probenecid's label (effective January 5, 2021) does not name avibactam/aztreonam in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Probenecid), Lannett Company, Inc., effective January 5, 2021 (SPL set ab497fd8-00c3-4364-b003-b39d21fbdf38), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Avibactam/aztreonam | Probenecid | |
|---|---|---|
| Labeled for | n/a | Gout |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.636 per tablet 500 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once