What the FDA labels say about taking them together
Atropine and ipratropium
Ipratropium's FDA label of January 8, 2026 names atropine in its contraindications section; the atropine labels PlainMeds reads (4) do not name ipratropium. The ipratropium label: “CONTRAINDICATIONS Ipratropium bromide nasal solution, 0.03% is contraindicated in patients with a history of hypersensitivity to atropine or its derivatives, or to any of the other ingredients.”
Check it at the source: the atropine FDA label on DailyMed (effective May 18, 2026, Hospira, Inc.); the ipratropium FDA label on DailyMed (effective January 8, 2026, Lupin Pharmaceuticals, Inc.).
What does the atropine label say about ipratropium?
Atropine's label (effective May 18, 2026) and its 3 other brand-application labels do not name ipratropium in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Atropine Sulfate), Hospira, Inc., effective May 18, 2026 (SPL set ad8916e7-206e-409e-2582-30d072845dd4), via openFDA; the full label on DailyMed
What does the ipratropium label say about atropine?
Ipratropium label, contraindicationsCONTRAINDICATIONS Ipratropium bromide nasal solution, 0.03% is contraindicated in patients with a history of hypersensitivity to atropine or its derivatives, or to any of the other ingredients.
Atrovent Hfa label (Boehringer Ingelheim Pharmaceuticals, Inc., November 5, 2025), contraindicationsHypersensitivity to ipratropium bromide or other ATROVENT HFA components Hypersensitivity to atropine or any of its derivatives Hypersensitivity to ipratropium bromide or other ATROVENT HFA components ( 4 ) Hypersensitivity to atropine or any of its derivatives
Source: FDA drug label (Atrovent Hfa, NDA021527), Boehringer Ingelheim Pharmaceuticals, Inc., effective November 5, 2025 (SPL set 170e98ef-5560-4068-be7d-e649068eb884), via openFDA
Source: FDA drug label (IPRATROPIUM BROMIDE), Lupin Pharmaceuticals, Inc., effective January 8, 2026 (SPL set 13a45df5-a8e3-41d6-91f4-773255b5a04b), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Atropine | Ipratropium | |
|---|---|---|
| Labeled for | n/a | COPD, Allergies, Cough and cold |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $7.74 per mL 1% eye drops | $0.111 per mL 0.02% solution |
| Shortage now | In shortage | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once