What the FDA labels say about taking them together
Atropine and clindamycin/tretinoin
Clindamycin/tretinoin's FDA label of May 15, 2026 names atropine in its warnings and precautions section; the atropine labels PlainMeds reads (4) do not name clindamycin/tretinoin.
Check it at the source: the atropine FDA label on DailyMed (effective May 18, 2026, Hospira, Inc.); the clindamycin/tretinoin FDA label on DailyMed (effective May 15, 2026, Bausch Health US, LLC).
What does the atropine label say about clindamycin/tretinoin?
Atropine's label (effective May 18, 2026) and its 3 other brand-application labels do not name clindamycin/tretinoin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Atropine Sulfate), Hospira, Inc., effective May 18, 2026 (SPL set ad8916e7-206e-409e-2582-30d072845dd4), via openFDA; the full label on DailyMed
What does the clindamycin/tretinoin label say about atropine?
Clindamycin/tretinoin label, warnings and precautionsAntiperistaltic agents such as opiates and diphenoxylate with atropine may prolong and/or worsen severe colitis.
Source: FDA drug label (ZIANA), Bausch Health US, LLC, effective May 15, 2026 (SPL set 78c329f9-f0c9-486d-9e54-0123699fb9e1), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Atropine | Clindamycin/tretinoin | |
|---|---|---|
| Labeled for | n/a | Acne |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $7.74 per mL 1% eye drops | $3.91 per gram 1.2%-0.025% |
| Shortage now | In shortage | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once