What the FDA labels say about taking them together
Atropine and benzoyl peroxide/clindamycin
Benzoyl peroxide/clindamycin's FDA label of January 31, 2026 names atropine in its warnings section; the atropine labels PlainMeds reads (4) do not name benzoyl peroxide/clindamycin.
Check it at the source: the atropine FDA label on DailyMed (effective May 18, 2026, Hospira, Inc.); the benzoyl peroxide/clindamycin FDA label on DailyMed (effective January 31, 2026, Glenmark Pharmaceuticals Inc., USA).
What does the atropine label say about benzoyl peroxide/clindamycin?
Atropine's label (effective May 18, 2026) and its 3 other brand-application labels do not name benzoyl peroxide/clindamycin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Atropine Sulfate), Hospira, Inc., effective May 18, 2026 (SPL set ad8916e7-206e-409e-2582-30d072845dd4), via openFDA; the full label on DailyMed
What does the benzoyl peroxide/clindamycin label say about atropine?
Benzoyl peroxide/clindamycin label, warningsANTIPERISTALTIC AGENTS SUCH AS OPIATES AND DIPHENOXYLATE WITH ATROPINE MAY PROLONG AND/OR WORSEN THE CONDITION.
Onexton label (Bausch Health US, LLC, July 23, 2025), warnings and precautionsAntiperistaltic agents such as opiates and diphenoxylate with atropine may prolong and/or worsen severe colitis.
Source: FDA drug label (Onexton, NDA050819), Bausch Health US, LLC, effective July 23, 2025 (SPL set 697e760a-c206-4565-8f4e-a8085e215827), via openFDA
Source: FDA drug label (clindamycin and benzoyl peroxide), Glenmark Pharmaceuticals Inc., USA, effective January 31, 2026 (SPL set 76795d1b-e1f2-4d1d-b42a-f1d4448c63c0), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Atropine | Benzoyl peroxide/clindamycin | |
|---|---|---|
| Labeled for | n/a | Acne |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $7.74 per mL 1% eye drops | $0.622 per gram 1-5% |
| Shortage now | In shortage | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once