What the FDA labels say about taking them together
Atovaquone/proguanil and warfarin
Atovaquone/proguanil's FDA label of June 10, 2026 names warfarin in its drug interactions section; the warfarin label PlainMeds reads does not name atovaquone/proguanil.
Check it at the source: the atovaquone/proguanil FDA label on DailyMed (effective June 10, 2026, GlaxoSmithKline LLC); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).
What does the atovaquone/proguanil label say about warfarin?
Atovaquone/proguanil label, drug interactionsProguanil may potentiate anticoagulant effect of warfarin and other coumarin-based anticoagulants.
Source: FDA drug label (MALARONE), GlaxoSmithKline LLC, effective June 10, 2026 (SPL set fc22e8d8-3bfb-4f70-a599-dd81262a4887), via openFDA; the full label on DailyMed
What does the warfarin label say about atovaquone/proguanil?
Warfarin's label (effective May 29, 2026) does not name atovaquone/proguanil in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Atovaquone/proguanil | Warfarin | |
|---|---|---|
| Labeled for | n/a | Blood clots (DVT and PE), Atrial fibrillation |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $1.49 per tablet 250-100 mg tablet | $0.093 per tablet 2 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once