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What the FDA labels say about taking them together

Atazanavir and felodipine

Atazanavir's FDA label of August 6, 2025 names felodipine in its drug interactions section; the felodipine label PlainMeds reads does not name atazanavir. The atazanavir label: “Caution is warranted. Dose titration of the calcium channel blocker should be considered. ECG monitoring is recommended.”

Check it at the source: the atazanavir FDA label on DailyMed (effective August 6, 2025, Aurobindo Pharma Limited); the felodipine FDA label on DailyMed (effective August 11, 2026, Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.).

What does the atazanavir label say about felodipine?

Atazanavir label, drug interactions

Concomitant Drug Class/Specific Drugs: felodipine, nifedipine, nicardipine, and verapamil; Effect on Concentration of Atazanavir or Concomitant Drug: ↑ calcium channel blocker; Clinical Comment: Caution is warranted. Dose titration of the calcium channel blocker should be considered. ECG monitoring is recommended.

Source: FDA drug label (Atazanavir Sulfate), Aurobindo Pharma Limited, effective August 6, 2025 (SPL set 7fbea274-d6b5-4faa-bbf0-05fefab42114), via openFDA; the full label on DailyMed

What does the felodipine label say about atazanavir?

Felodipine's label (effective August 11, 2026) does not name atazanavir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (FELODIPINE), Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc., effective August 11, 2026 (SPL set 0bef7cf2-012b-4804-ac93-0a8b333035db), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

4Atazanavir generic labelers
14Felodipine generic labelers
AtazanavirFelodipine
Labeled forHIVHigh blood pressure
Boxed warningNoNo
Pharmacy cost (NADAC)$2.23 per capsule 300 mg capsule$0.123 per tablet 5 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?