What the FDA labels say about taking them together
Asenapine and quinidine
Asenapine's FDA label of January 31, 2025 names quinidine in its warnings and precautions section; the quinidine label PlainMeds reads does not name asenapine.
Check it at the source: the asenapine FDA label on DailyMed (effective January 31, 2025, Allergan, Inc.); the quinidine FDA label on DailyMed (effective February 1, 2018, Sun Pharmaceutical Industries, Inc.).
What does the asenapine label say about quinidine?
Asenapine label, warnings and precautionsThe use of SAPHRIS should be avoided in combination with other drugs known to prolong QTc including Class 1A antiarrhythmics (e.g., quinidine, procainamide) or Class 3 antiarrhythmics (e.g., amiodarone, sotalol), antipsychotic medications (e.g., ziprasidone, chlorpromazine, thioridazine), and antibiotics (e.g., gatifloxacin, moxifloxacin).
Source: FDA drug label (Secuado, NDA212268), Noven Therapeutics, LLC, effective January 30, 2025 (SPL set 685eaf44-5944-4f38-afba-0a4fc0b3462b), via openFDA
Source: FDA drug label (SAPHRIS), NDA022117 (Abbvie), as published by Allergan, Inc., effective January 31, 2025 (SPL set 5429f134-839f-4ffc-9944-55f51238def8), via openFDA; the full label on DailyMed
What does the quinidine label say about asenapine?
Quinidine's label (effective February 1, 2018) does not name asenapine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Quinidine Gluconate), Sun Pharmaceutical Industries, Inc., effective February 1, 2018 (SPL set 5023f053-fcc4-4c2c-aa59-9ec198ad185e), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Asenapine | Quinidine | |
|---|---|---|
| Labeled for | Schizophrenia, Bipolar disorder | Atrial fibrillation |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $2.63 per tablet 10 mg tablet sl | $4.92 per tablet 324 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once