What the FDA labels say about taking them together
Arsenic trioxide and ziprasidone
Ziprasidone's FDA label of July 20, 2026 names arsenic trioxide in its contraindications section; the arsenic trioxide labels PlainMeds reads (2) do not name ziprasidone. The ziprasidone label: “… sparfloxacin, gatifloxacin, moxifloxacin, halofantrine, mefloquine, pentamidine, arsenic trioxide, levomethadyl acetate, dolasetron mesylate, probucol or tacrolimus. …”
Check it at the source: the arsenic trioxide FDA label on DailyMed (effective July 23, 2021, Amneal Pharmaceuticals LLC); the ziprasidone FDA label on DailyMed (effective July 20, 2026, Apotex Corp.).
What does the arsenic trioxide label say about ziprasidone?
Arsenic trioxide's label (effective July 23, 2021) and its 1 other brand-application label do not name ziprasidone in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Arsenic Trioxide), Amneal Pharmaceuticals LLC, effective July 23, 2021 (SPL set 5845022e-8c01-451b-ae49-a28e58c5f845), via openFDA; the full label on DailyMed
What does the ziprasidone label say about arsenic trioxide?
Ziprasidone label, contraindicationsTherefore, ziprasidone should not be given with: dofetilide, sotalol, quinidine, other Class Ia and III anti-arrhythmics, mesoridazine, thioridazine, chlorpromazine, droperidol, pimozide, sparfloxacin, gatifloxacin, moxifloxacin, halofantrine, mefloquine, pentamidine, arsenic trioxide, levomethadyl acetate, dolasetron mesylate, probucol or tacrolimus. other drugs that have demonstrated QT prolongation as one of their pharmacodynamic effects and have this effect described in the full prescribing information as a contraindication or a boxed or bolded warning [see Warnings and Precautions (5.3) ].
Source: FDA drug label (ziprasidone hydrochloride), Apotex Corp., effective July 20, 2026 (SPL set ccfd5ba2-7271-f3dd-4c98-7418c1a4b54a), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Arsenic trioxide | Ziprasidone | |
|---|---|---|
| Labeled for | Leukemia, lymphoma and myeloma | Bipolar disorder, Schizophrenia |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | n/a | $0.269 per capsule 20 mg capsule |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once