What the FDA labels say about taking them together
Amphetamine and linezolid
Amphetamine's FDA label (Dyanavel Xr) of February 24, 2026 names linezolid in its contraindications section; the linezolid labels PlainMeds reads (3) do not name amphetamine. The amphetamine label: “Patients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs, because of an increased risk of hypertensive crisis.”
Check it at the source: the amphetamine FDA label on DailyMed (effective August 20, 2026, Aurolife Pharma, LLC); the linezolid FDA label on DailyMed (effective June 19, 2026, Hospira, Inc.).
What does the amphetamine label say about linezolid?
Dyanavel Xr label (NextWave Pharmaceuticals, Inc, February 24, 2026), contraindicationsPatients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive crisis [ see Warnings and Precautions (5.7), Drug Interactions (7.1) ].
Source: FDA drug label (Dyanavel Xr, NDA208147), NextWave Pharmaceuticals, Inc, effective February 24, 2026 (SPL set ae304b29-0b40-40ec-ad0d-76b742d4a9b9), via openFDA
Source: FDA drug label (Adzenys Xr-Odt, NDA204326), Neos Therapeutics Brands, LLC, effective May 6, 2026 (SPL set c1179269-00b5-48ea-972d-31e614e99b7e), via openFDA
Source: FDA drug label (Amphetamine Sulfate), Aurolife Pharma, LLC, effective August 20, 2026 (SPL set 20735c2e-6304-425f-a4e4-584f6f90d6a0), via openFDA; the full label on DailyMed
What does the linezolid label say about amphetamine?
Linezolid's label (effective June 19, 2026) and its 2 other brand-application labels do not name amphetamine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Linezolid), Hospira, Inc., effective June 19, 2026 (SPL set c401f1a8-cc37-461b-bfef-f2e156629bf8), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Amphetamine | Linezolid | |
|---|---|---|
| Labeled for | ADHD | Bacterial infections |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.449 per tablet 10 mg tablet | $1.44 per tablet 600 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once