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What the FDA labels say about taking them together

Amphetamine and chlorpromazine

Amphetamine's FDA label of August 20, 2026 names chlorpromazine in its drug interactions section; the chlorpromazine label PlainMeds reads does not name amphetamine.

Check it at the source: the amphetamine FDA label on DailyMed (effective August 20, 2026, Aurolife Pharma, LLC); the chlorpromazine FDA label on DailyMed (effective May 12, 2026, Amneal Pharmaceuticals NY LLC).

What does the amphetamine label say about chlorpromazine?

Amphetamine label, drug interactions

Chlorpromazine Chlorpromazine blocks dopamine and norepinephrine reuptake, thus inhibiting the central stimulant effects of amphetamine, and can be used to treat amphetamine poisoning.

Source: FDA drug label (Amphetamine Sulfate), Aurolife Pharma, LLC, effective August 20, 2026 (SPL set 20735c2e-6304-425f-a4e4-584f6f90d6a0), via openFDA; the full label on DailyMed

What does the chlorpromazine label say about amphetamine?

Chlorpromazine's label (effective May 12, 2026) does not name amphetamine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (CHLORPROMAZINE HYDROCHLORIDE), Amneal Pharmaceuticals NY LLC, effective May 12, 2026 (SPL set aa086a21-de85-4b03-af58-49b70acf8cf0), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

13Amphetamine generic labelers
33Chlorpromazine generic labelers
AmphetamineChlorpromazine
Labeled forADHDSchizophrenia, Nausea and vomiting
Boxed warningYesYes
Pharmacy cost (NADAC)$0.449 per tablet 10 mg tablet$0.552 per tablet 100 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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