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What the FDA labels say about taking them together

Amiodarone and talazoparib

Talazoparib's FDA label of April 10, 2026 names amiodarone in its drug interactions section; the amiodarone labels PlainMeds reads (2) do not name talazoparib. The talazoparib label: “Drugs on TALZENNA Effect of P-gp Inhibitors Breast Cancer Avoid coadministration of TALZENNA with the following P-gp inhibitors: itraconazole, amiodarone, carvedilol, clarithromycin, itraconazole, and verapamil.”

Check it at the source: the amiodarone FDA label on DailyMed (effective December 9, 2025, Chartwell RX, LLC); the talazoparib FDA label on DailyMed (effective April 10, 2026, Pfizer Laboratories Div Pfizer Inc).

What does the amiodarone label say about talazoparib?

Amiodarone's label (effective December 9, 2025) and its 1 other brand-application label do not name talazoparib in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Amiodarone Hydrochloride), Chartwell RX, LLC, effective December 9, 2025 (SPL set 5520f11d-968d-4f4f-bf57-d14369c0d746), via openFDA; the full label on DailyMed

What does the talazoparib label say about amiodarone?

Talazoparib label, drug interactions

Drugs on TALZENNA Effect of P-gp Inhibitors Breast Cancer Avoid coadministration of TALZENNA with the following P-gp inhibitors: itraconazole, amiodarone, carvedilol, clarithromycin, itraconazole, and verapamil.

Source: FDA drug label (Talzenna), Pfizer Laboratories Div Pfizer Inc, effective April 10, 2026 (SPL set c6fd147f-a77e-4a0b-9280-e82ecc41b4be), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

32Amiodarone generic labelers
0Talazoparib generic labelers
AmiodaroneTalazoparib
Labeled forn/aBreast cancer, Prostate cancer
Boxed warningYesNo
Pharmacy cost (NADAC)$0.122 per tablet 200 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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