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What the FDA labels say about taking them together

Amiodarone and haloperidol

Haloperidol's FDA label (Haloperidol Decanoate) of February 19, 2025 names amiodarone in its drug interactions section; the amiodarone labels PlainMeds reads (2) do not name haloperidol.

Check it at the source: the amiodarone FDA label on DailyMed (effective December 9, 2025, Chartwell RX, LLC); the haloperidol FDA label on DailyMed (effective April 23, 2026, PD-Rx Pharmaceuticals, Inc.).

What does the amiodarone label say about haloperidol?

Amiodarone's label (effective December 9, 2025) and its 1 other brand-application label do not name haloperidol in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Amiodarone Hydrochloride), Chartwell RX, LLC, effective December 9, 2025 (SPL set 5520f11d-968d-4f4f-bf57-d14369c0d746), via openFDA; the full label on DailyMed

What does the haloperidol label say about amiodarone?

Haloperidol Decanoate label (Patriot Pharmaceuticals LLC, February 19, 2025), drug interactions

Class 3 antiarrhythmics (e.g., amiodarone, sotalol); and other drugs such as citalopram, erythromycin, levofloxacin, methadone, and ziprasidone.

Source: FDA drug label (Haloperidol Decanoate, NDA018701), Patriot Pharmaceuticals LLC, effective February 19, 2025 (SPL set 9f0f42a8-5f7c-4be7-93ef-3ec225502cc6), via openFDA

Source: FDA drug label (Haloperidol), PD-Rx Pharmaceuticals, Inc., effective April 23, 2026 (SPL set 533b0b4c-cbd6-4ec0-a333-8b04b5b43a1d), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

32Amiodarone generic labelers
41Haloperidol generic labelers
AmiodaroneHaloperidol
Labeled forn/aSchizophrenia
Boxed warningYesYes
Pharmacy cost (NADAC)$0.122 per tablet 200 mg tablet$15.60 per mL 100 mg/mL vial
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?