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What the FDA labels say about taking them together

Amiodarone and foscarnet

Foscarnet's FDA label of December 11, 2025 names amiodarone in its drug interactions section; the amiodarone labels PlainMeds reads (2) do not name foscarnet. The foscarnet label: “Abnormal renal function has been observed in clinical practice during the use of FOSCAVIR and ritonavir, or FOSCAVIR, ritonavir, and saquinavir. …”

Check it at the source: the amiodarone FDA label on DailyMed (effective December 9, 2025, Chartwell RX, LLC); the foscarnet FDA label on DailyMed (effective December 11, 2025, Clinigen Limited).

What does the amiodarone label say about foscarnet?

Amiodarone's label (effective December 9, 2025) and its 1 other brand-application label do not name foscarnet in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Amiodarone Hydrochloride), Chartwell RX, LLC, effective December 9, 2025 (SPL set 5520f11d-968d-4f4f-bf57-d14369c0d746), via openFDA; the full label on DailyMed

What does the foscarnet label say about amiodarone?

Foscarnet label, drug interactions

Abnormal renal function has been observed in clinical practice during the use of FOSCAVIR and ritonavir, or FOSCAVIR, ritonavir, and saquinavir. (See DOSAGE and ADMINISTRATION. ) Because of the risk of QT prolongation and the potential for torsades de pointes, the use of FOSCAVIR should be avoided in combination with agents known to prolong the QT interval including Class IA (e.g., quinidine or procainamide) or Class III (e.g., dofetilide, amiodarone, sotalol) antiarrhythmic agents, phenothiazines, tricyclic antidepressants, and certain macrolides and fluoroquinolones.

Source: FDA drug label (Foscavir), Clinigen Limited, effective December 11, 2025 (SPL set 90e3da4e-3b1f-428b-99ca-e4bed1c80028), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

32Amiodarone generic labelers
9Foscarnet generic labelers
AmiodaroneFoscarnet
Labeled forn/an/a
Boxed warningYesYes
Pharmacy cost (NADAC)$0.122 per tablet 200 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?