What the FDA labels say about taking them together
Amiodarone and fosamprenavir
Fosamprenavir's FDA label of September 15, 2023 names amiodarone in its drug interactions section; the amiodarone labels PlainMeds reads (2) do not name fosamprenavir. The fosamprenavir label: “Therapeutic concentration monitoring, if available, is recommended for antiarrhythmics.”
Check it at the source: the amiodarone FDA label on DailyMed (effective December 9, 2025, Chartwell RX, LLC); the fosamprenavir FDA label on DailyMed (effective September 15, 2023, Mylan Pharmaceuticals Inc.).
What does the amiodarone label say about fosamprenavir?
Amiodarone's label (effective December 9, 2025) and its 1 other brand-application label do not name fosamprenavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Amiodarone Hydrochloride), Chartwell RX, LLC, effective December 9, 2025 (SPL set 5520f11d-968d-4f4f-bf57-d14369c0d746), via openFDA; the full label on DailyMed
What does the fosamprenavir label say about amiodarone?
Fosamprenavir label, drug interactionsConcomitant Drug Class/Drug Name: Antiarrhythmics: Amiodarone, disopyramide, lidocaine (systemic), and quinidine; Effect on Concentration of Amprenavir or Concomitant Drug: ↑ Antiarrhythmics; Clinical Comment: Therapeutic concentration monitoring, if available, is recommended for antiarrhythmics.
Source: FDA drug label (Fosamprenavir Calcium), Mylan Pharmaceuticals Inc., effective September 15, 2023 (SPL set 3a1424d8-844c-4e24-9ebd-b2c2b61b61a3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Amiodarone | Fosamprenavir | |
|---|---|---|
| Labeled for | n/a | HIV |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.122 per tablet 200 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once