What the FDA labels say about taking them together
Amiodarone and etrasimod arginine
Etrasimod arginine's FDA label of August 18, 2025 names amiodarone in its drug interactions section; the amiodarone labels PlainMeds reads (2) do not name etrasimod arginine. The etrasimod arginine label: “Prevention or Management; Seek the advice of a cardiologist before initiating VELSIPITY treatment with Class Ia, Class III anti-arrhythmic drugs, or other drugs that prolong the QT interval.”
Check it at the source: the amiodarone FDA label on DailyMed (effective December 9, 2025, Chartwell RX, LLC); the etrasimod arginine FDA label on DailyMed (effective August 18, 2025, Pfizer Laboratories Div Pfizer Inc).
What does the amiodarone label say about etrasimod arginine?
Amiodarone's label (effective December 9, 2025) and its 1 other brand-application label do not name etrasimod arginine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Amiodarone Hydrochloride), Chartwell RX, LLC, effective December 9, 2025 (SPL set 5520f11d-968d-4f4f-bf57-d14369c0d746), via openFDA; the full label on DailyMed
What does the etrasimod arginine label say about amiodarone?
Etrasimod arginine label, drug interactionsPrevention or Management; Seek the advice of a cardiologist before initiating VELSIPITY treatment with Class Ia (e.g., quinidine, procainamide), Class III anti-arrhythmic drugs (e.g., amiodarone, sotalol), or other drugs that prolong the QT interval.
Source: FDA drug label (Velsipity), Pfizer Laboratories Div Pfizer Inc, effective August 18, 2025 (SPL set 65171e4a-d136-4abc-b08c-c40c1b486ff6), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Amiodarone | Etrasimod arginine | |
|---|---|---|
| Labeled for | n/a | Crohn's disease and ulcerative colitis |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.122 per tablet 200 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once