Cimetidine · larger labeled portfolio than Amiodarone
SPL labels Amiodarone + Cimetidine as minor; Amiodarone 29 / Cimetidine 63 in that band.
Mechanism on file: Cimetidine blocks the enzymes that break down amiodarone in your body. This causes the levels of amiodarone in your blood to rise, which could increase the risk of side effects.
FDA SPL severity: Minor
Amiodarone + Cimetidine · SPL mechanism field
Cimetidine blocks the enzymes that break down amiodarone in your body. This causes the levels of amiodarone in your blood to rise, which could increase the risk of side effects.
Minor band excerpt · Amiodarone with Cimetidine
Pharmacokinetic Interactions CYP450 Inhibitors grapefruit juice, certain fluoroquinolone and macrolide antibiotics, azole antifungals, cimetidine, certain protease inhibitors Increased exposure of amiodarone.
Amiodarone · 29 minor + 42 total pairs
- Atenolol minor
- Atorvastatin minor
- Carvedilol minor
- Cholestyramine minor
Cimetidine · 77 SPL pairs (broader portfolio than Amiodarone)
- Albendazole minor
- Alogliptin minor
- Alosetron minor
- Alprazolam minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.