What the FDA labels say about taking them together
Amiodarone and cholestyramine
Amiodarone's FDA label of December 9, 2025 names cholestyramine in its drug interactions section; the cholestyramine label PlainMeds reads does not name amiodarone. The amiodarone label: “Reduced amiodarone serum levels”
Check it at the source: the amiodarone FDA label on DailyMed (effective December 9, 2025, Chartwell RX, LLC); the cholestyramine FDA label on DailyMed (effective August 20, 2026, AiPing Pharmaceutical, Inc.).
What does the amiodarone label say about cholestyramine?
Amiodarone label, drug interactionsConcomitant Drug/Class/Name: Cholestyramine; Examples: Reduced amiodarone serum levels.
Source: FDA drug label (Nexterone, NDA022325), Baxter Healthcare Corporation, effective April 16, 2024 (SPL set e9108958-b8d7-4fba-87c3-9a32990de551), via openFDA
Source: FDA drug label (Amiodarone Hydrochloride), Chartwell RX, LLC, effective December 9, 2025 (SPL set 5520f11d-968d-4f4f-bf57-d14369c0d746), via openFDA; the full label on DailyMed
What does the cholestyramine label say about amiodarone?
Cholestyramine's label (effective August 20, 2026) does not name amiodarone in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Cholestyramine), AiPing Pharmaceutical, Inc., effective August 20, 2026 (SPL set 214ea05f-de81-4026-9df9-4ce3820668ee), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Amiodarone | Cholestyramine | |
|---|---|---|
| Labeled for | n/a | High cholesterol |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.122 per tablet 200 mg tablet | $0.834 per packet Cholestyramine packet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once