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What the FDA labels say about taking them together

Amiodarone and anagrelide

Anagrelide's FDA label of April 8, 2026 names amiodarone in its drug interactions section; the amiodarone labels PlainMeds reads (2) do not name anagrelide. The anagrelide label: “Drugs that Prolong QT Avoid use of AGRYLIN in patients taking medications that may prolong QT interval.”

Check it at the source: the amiodarone FDA label on DailyMed (effective December 9, 2025, Chartwell RX, LLC); the anagrelide FDA label on DailyMed (effective April 8, 2026, Takeda Pharmaceuticals America, Inc.).

What does the amiodarone label say about anagrelide?

Amiodarone's label (effective December 9, 2025) and its 1 other brand-application label do not name anagrelide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Amiodarone Hydrochloride), Chartwell RX, LLC, effective December 9, 2025 (SPL set 5520f11d-968d-4f4f-bf57-d14369c0d746), via openFDA; the full label on DailyMed

What does the anagrelide label say about amiodarone?

Anagrelide label, drug interactions

Drugs that Prolong QT Avoid use of AGRYLIN in patients taking medications that may prolong QT interval (including, but not limited to, chloroquine, clarithromycin, haloperidol, methadone, moxifloxacin, amiodarone, disopyramide, procainamide, and pimozide) [see Warnings and Precautions (5.1) and Clinical Pharmacology (12.2) ].

Source: FDA drug label (Agrylin), Takeda Pharmaceuticals America, Inc., effective April 8, 2026 (SPL set cb960074-99c1-4a73-941f-f0644a7ec219), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

32Amiodarone generic labelers
3Anagrelide generic labelers
AmiodaroneAnagrelide
Labeled forn/an/a
Boxed warningYesNo
Pharmacy cost (NADAC)$0.122 per tablet 200 mg tablet$0.729 per capsule 0.5 mg capsule
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?