What the FDA labels say about taking them together
Amikacin and paromomycin
Amikacin's FDA label of December 10, 2025 names paromomycin in its boxed warning section; the paromomycin label PlainMeds reads does not name amikacin.
Check it at the source: the amikacin FDA label on DailyMed (effective December 10, 2025, Qilu Pharmaceutical Co., Ltd.); the paromomycin FDA label on DailyMed (effective November 13, 2025, Waylis Therapeutics LLC).
What does the amikacin label say about paromomycin?
Amikacin label, boxed warningConcurrent and/or sequential systemic, oral or topical use of other neurotoxic or nephrotoxic products, particularly bacitracin, cisplatin, amphotericin B, cephaloridine, paromomycin, viomycin, polymyxin B, colistin, vancomycin, or other aminoglycosides should be avoided.
Source: FDA drug label (Amikacin Sulfate), Qilu Pharmaceutical Co., Ltd., effective December 10, 2025 (SPL set 20fa61ef-11e2-4d01-82ea-b5412cefaead), via openFDA; the full label on DailyMed
What does the paromomycin label say about amikacin?
Paromomycin's label (effective November 13, 2025) does not name amikacin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Humatin), ANDA065173 (Heritage), as published by Waylis Therapeutics LLC, effective November 13, 2025 (SPL set a725f022-ec3c-430d-8021-96c861b9893c), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Amikacin | Paromomycin | |
|---|---|---|
| Labeled for | Bacterial infections | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $2.33 per mL 500 mg/2 mL vial | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once