What the FDA labels say about taking them together
Amantadine and glycopyrrolate
Glycopyrrolate's FDA label (Cuvposa) of December 19, 2024 names amantadine in its drug interactions section; the amantadine labels PlainMeds reads (2) do not name glycopyrrolate. The glycopyrrolate label: “Effects of glycopyrrolate may be increased with concomitant administration of amantadine.”
Check it at the source: the amantadine FDA label on DailyMed (effective January 30, 2026, Strides Pharma Inc.); the glycopyrrolate FDA label on DailyMed (effective October 9, 2025, Hikma Pharmaceuticals USA Inc.).
What does the amantadine label say about glycopyrrolate?
Amantadine's label (effective January 30, 2026) and its 1 other brand-application label do not name glycopyrrolate in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Amantadine Hydrochloride), Strides Pharma Inc., effective January 30, 2026 (SPL set e4d8f36f-d668-4728-8dca-b1c22bd9aedb), via openFDA; the full label on DailyMed
What does the glycopyrrolate label say about amantadine?
Cuvposa label (Merz Pharmaceuticals, LLC, December 19, 2024), drug interactionsEffects of glycopyrrolate may be increased with concomitant administration of amantadine.
Source: FDA drug label (Cuvposa, NDA022571), Merz Pharmaceuticals, LLC, effective December 19, 2024 (SPL set d200bd44-9856-4104-a29e-a4cca3db6737), via openFDA
Source: FDA drug label (Glycopyrrolate), Hikma Pharmaceuticals USA Inc., effective October 9, 2025 (SPL set 960d2dd0-008d-4ec1-ba2e-9388b28b23e2), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Amantadine | Glycopyrrolate | |
|---|---|---|
| Labeled for | Influenza, Parkinson's disease | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.143 per capsule 100 mg capsule | $1.51 per mL 0.2 mg/mL vial |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once