What the FDA labels say about taking them together
Alprostadil and warfarin
Alprostadil's FDA label (Caverject) of May 13, 2024 names warfarin in its warnings and precautions section; the warfarin label PlainMeds reads does not name alprostadil. The alprostadil label: “Injection site bleeding may occur in patients taking anticoagulants, such as warfarin or heparin.”
Check it at the source: the alprostadil FDA label on DailyMed (effective March 27, 2024, Endo USA, Inc.); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).
What does the alprostadil label say about warfarin?
Caverject label (Pharmacia & Upjohn Company LLC, May 13, 2024), warnings and precautionsInjection site bleeding may occur in patients taking anticoagulants, such as warfarin or heparin.
Source: FDA drug label (Caverject, NDA020379), Pharmacia & Upjohn Company LLC, effective May 13, 2024 (SPL set a295fc1e-d82c-4f44-bc2d-a552bf594c98), via openFDA
Source: FDA drug label (Edex), Endo USA, Inc., effective March 27, 2024 (SPL set e8b8ec8d-1318-43e4-a182-446e9f9579de), via openFDA; the full label on DailyMed
What does the warfarin label say about alprostadil?
Warfarin's label (effective May 29, 2026) does not name alprostadil in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Alprostadil | Warfarin | |
|---|---|---|
| Labeled for | Erectile dysfunction | Blood clots (DVT and PE), Atrial fibrillation |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $106.24 per kit 20 mcg kit | $0.093 per tablet 2 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once