What the FDA labels say about taking them together
Aliskiren and furosemide
Aliskiren's FDA label of March 7, 2024 names furosemide in its drug interactions section; the furosemide labels PlainMeds reads (4) do not name aliskiren. The aliskiren label: “Oral coadministration of aliskiren and furosemide reduced exposure to furosemide.”
Check it at the source: the aliskiren FDA label on DailyMed (effective March 7, 2024, LXO US Inc.); the furosemide FDA label on DailyMed (effective September 30, 2025, Validus Pharmaceuticals LLC).
What does the aliskiren label say about furosemide?
Aliskiren label, drug interactionsOral coadministration of aliskiren and furosemide reduced exposure to furosemide.
Source: FDA drug label (Tekturna), NDA021985 (Lxo Ireland), as published by LXO US Inc., effective March 7, 2024 (SPL set 3dd61fa5-1620-4ebf-bbdb-ede29b92fce2), via openFDA; the full label on DailyMed
What does the furosemide label say about aliskiren?
Furosemide's label (effective September 30, 2025) and its 3 other brand-application labels do not name aliskiren in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Lasix), Validus Pharmaceuticals LLC, effective September 30, 2025 (SPL set 2c9b4d8f-0770-482d-a9e6-9c616a440b1a), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Aliskiren | Furosemide | |
|---|---|---|
| Labeled for | High blood pressure | Heart failure, High blood pressure, Edema (fluid retention) |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $3.94 per tablet 150 mg tablet | $0.490 per mL 20 mg/2 mL vial |
| Shortage now | No current entry | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once