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What the FDA labels say about taking them together

Albendazole and fosphenytoin

Fosphenytoin's FDA label of May 18, 2025 names albendazole in its drug interactions section; the albendazole label PlainMeds reads does not name fosphenytoin. The fosphenytoin label: “Interacting Agent: Other; Examples: Albendazole, chlorpropamide, clozapine, cyclosporine, digoxin, disopyramide, folic acid, methadone, mexiletine, praziquantel, quetiapine”

Check it at the source: the albendazole FDA label on DailyMed (effective September 30, 2019, Amneal Pharmaceuticals of New York LLC); the fosphenytoin FDA label on DailyMed (effective May 18, 2025, Pfizer Laboratories Div Pfizer Inc).

What does the albendazole label say about fosphenytoin?

Albendazole's label (effective September 30, 2019) does not name fosphenytoin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Albendazole), NDA020666 (Impax Labs Inc), as published by Amneal Pharmaceuticals of New York LLC, effective September 30, 2019 (SPL set 06b5eefc-0b95-4862-b9b6-770063f2adf0), via openFDA; the full label on DailyMed

What does the fosphenytoin label say about albendazole?

Fosphenytoin label, drug interactions

Interacting Agent: Other; Examples: Albendazole (decreases active metabolite), chlorpropamide, clozapine, cyclosporine, digoxin, disopyramide, folic acid, methadone, mexiletine, praziquantel, quetiapine

Source: FDA drug label (CEREBYX), NDA020450 (Parke Davis), as published by Pfizer Laboratories Div Pfizer Inc, effective May 18, 2025 (SPL set de5a6711-4abb-4c3d-a18b-266b094ace11), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

8Albendazole generic labelers
7Fosphenytoin generic labelers
AlbendazoleFosphenytoin
Labeled forn/aSeizures and epilepsy
Boxed warningNoYes
Pharmacy cost (NADAC)$4.15 per tablet 200 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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