What the FDA labels say about taking them together
Adefovir dipivoxil and vancomycin
Adefovir dipivoxil's FDA label of July 22, 2025 names vancomycin in its warnings and precautions section; the vancomycin labels PlainMeds reads (4) do not name adefovir dipivoxil. The adefovir dipivoxil label: “… concomitant nephrotoxic agents such as cyclosporine, tacrolimus, aminoglycosides, vancomycin and non-steroidal anti-inflammatory drugs.”
Check it at the source: the adefovir dipivoxil FDA label on DailyMed (effective July 22, 2025, Apotex Corp.); the vancomycin FDA label on DailyMed (effective June 7, 2024, Mylan Institutional LLC).
What does the adefovir dipivoxil label say about vancomycin?
Adefovir dipivoxil label, warnings and precautionsHowever, this is of special importance in patients at risk of or having underlying renal dysfunction and patients taking concomitant nephrotoxic agents such as cyclosporine, tacrolimus, aminoglycosides, vancomycin and non-steroidal anti-inflammatory drugs [See Adverse Reactions (6.2) and Clinical Pharmacology (12.3) ].
Source: FDA drug label (Adefovir dipivoxil), Apotex Corp., effective July 22, 2025 (SPL set 08e07fae-3191-b6a3-c894-d3a8cc53923f), via openFDA; the full label on DailyMed
What does the vancomycin label say about adefovir dipivoxil?
Vancomycin's label (effective June 7, 2024) and its 3 other brand-application labels do not name adefovir dipivoxil in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Vancomycin Hydrochloride), Mylan Institutional LLC, effective June 7, 2024 (SPL set caf22ccb-df75-45ea-a1d0-ccb2d37272fb), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Adefovir dipivoxil | Vancomycin | |
|---|---|---|
| Labeled for | Hepatitis B | Bacterial infections, Diarrhea |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $21.73 per tablet 10 mg tablet | $1.33 per capsule 125 mg capsule |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once