What the FDA labels say about taking them together
Acitretin and sarecycline
Sarecycline's FDA label of June 5, 2024 names acitretin in its drug interactions section; the acitretin label PlainMeds reads does not name sarecycline. The sarecycline label: “Drugs on SEYSARA Oral Retinoids Tetracyclines may cause increased intracranial pressure as do oral retinoids, including isotretinoin and acitretin.”
Check it at the source: the acitretin FDA label on DailyMed (effective August 5, 2026, Sigmapharm Laboratories, LLC); the sarecycline FDA label on DailyMed (effective June 5, 2024, Almirall, LLC).
What does the acitretin label say about sarecycline?
Acitretin's label (effective August 5, 2026) does not name sarecycline in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (ACITRETIN), Sigmapharm Laboratories, LLC, effective August 5, 2026 (SPL set a6546625-acb8-460e-b34e-f795bfb3680a), via openFDA; the full label on DailyMed
What does the sarecycline label say about acitretin?
Sarecycline label, drug interactionsDrugs on SEYSARA Oral Retinoids Tetracyclines may cause increased intracranial pressure as do oral retinoids, including isotretinoin and acitretin [see Warnings and Precautions ( 5.4 )].
Source: FDA drug label (Seysara), Almirall, LLC, effective June 5, 2024 (SPL set b200957c-3004-4988-be97-9fd619a83649), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Acitretin | Sarecycline | |
|---|---|---|
| Labeled for | Psoriasis | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $2.59 per capsule 10 mg capsule | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once