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What the FDA labels say about taking them together

Abiraterone and radium ra 223 dichloride

Abiraterone's FDA label of March 28, 2025 names radium ra 223 dichloride in its warnings and precautions section, and radium ra 223 dichloride's label names abiraterone too. The radium ra 223 dichloride label: “Increased Fractures and Mortality in Combination with Abiraterone plus Prednisone/Prednisolone:”

Check it at the source: the abiraterone FDA label on DailyMed (effective March 28, 2025, Janssen Biotech, Inc.); the radium ra 223 dichloride FDA label on DailyMed (effective March 2, 2026, Bayer HealthCare Pharmaceuticals Inc.).

What does the abiraterone label say about radium ra 223 dichloride?

Abiraterone label, warnings and precautions

Monitor liver function and modify, interrupt, or discontinue ZYTIGA dosing as recommended. ( 5.3 ) Increased fractures and mortality in combination with radium Ra 223 dichloride:

Source: FDA drug label (Yonsa, NDA210308), Sun Pharmaceutical Industries, Inc., effective June 8, 2026 (SPL set b8967e10-f768-47ce-ac9e-2324c8390132), via openFDA

Source: FDA drug label (Zytiga), Janssen Biotech, Inc., effective March 28, 2025 (SPL set 4e338e89-3cf2-48eb-b6e2-a06c608c6513), via openFDA; the full label on DailyMed

What does the radium ra 223 dichloride label say about abiraterone?

Radium ra 223 dichloride label, warnings and precautions

Increased Fractures and Mortality in Combination with Abiraterone plus Prednisone/Prednisolone:

Source: FDA drug label (Xofigo), Bayer HealthCare Pharmaceuticals Inc., effective March 2, 2026 (SPL set a398400e-bd31-41a9-9696-4f7c06569ede), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

23Abiraterone generic labelers
0Radium ra 223 dichloride generic labelers
AbirateroneRadium ra 223 dichloride
Labeled forProstate cancerProstate cancer
Boxed warningNoNo
Pharmacy cost (NADAC)$0.774 per tablet 250 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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