What the FDA labels say about taking them together
Abiraterone and prednisolone
Abiraterone's FDA label of March 28, 2025 names prednisolone in its warnings and precautions section; the prednisolone labels PlainMeds reads (4) do not name abiraterone. The abiraterone label: “Use of ZYTIGA plus prednisone/prednisolone in combination with radium Ra 223 dichloride is not recommended.”
Check it at the source: the abiraterone FDA label on DailyMed (effective March 28, 2025, Janssen Biotech, Inc.); the prednisolone FDA label on DailyMed (effective June 25, 2026, PAI Holdings, LLC dba PAI Pharma).
What does the abiraterone label say about prednisolone?
Abiraterone label, warnings and precautionsUse of ZYTIGA plus prednisone/prednisolone in combination with radium Ra 223 dichloride is not recommended.
Source: FDA drug label (Zytiga), Janssen Biotech, Inc., effective March 28, 2025 (SPL set 4e338e89-3cf2-48eb-b6e2-a06c608c6513), via openFDA; the full label on DailyMed
What does the prednisolone label say about abiraterone?
Prednisolone's label (effective June 25, 2026) and its 3 other brand-application labels do not name abiraterone in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (PrednisoLONE Sodium Phosphate), PAI Holdings, LLC dba PAI Pharma, effective June 25, 2026 (SPL set d1f937e7-fed5-4079-bd52-5d930b34ae9f), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Abiraterone | Prednisolone | |
|---|---|---|
| Labeled for | Prostate cancer | Anemia, Leukemia, lymphoma and myeloma, Multiple sclerosis, Osteoarthritis, Asthma, Allergies, Herpes and shingles, Crohn's disease and ulcerative colitis, Eczema (atopic dermatitis), Organ transplant rejection |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.774 per tablet 250 mg tablet | $4.72 per mL 1% eye drop |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once