Abatacept and Golimumab Interaction
Drug interaction information between Abatacept and Golimumab.
Abatacept and Golimumab have a documented moderate interaction in FDA labeling.
FDA drug labeling documents a moderate-severity interaction between Abatacept and Golimumab. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Both of these drugs weaken the immune system to treat inflammation. Using them together makes it much harder for your body to fight off serious infections without providing extra help for your condition.
FDA Label Information
7 DRUG INTERACTIONS Biologics, including abatacept and anakinra: Increased risk of serious infections ( 5.1 , 5.6 , 5.7 , 5.8 , 7.2 ). 7.2 Biologic Products for RA, PsA, AS, and pJIA An increased risk of serious infections has been seen in clinical RA studies of other TNF-blockers used in combination with anakinra or abatacept, with no added benefit; therefore, use of SIMPONI ARIA with other biologic products, including abatacept or anakinra, is not recommended [see Warnings and Precautions (5.6 and 5.7) ] .
Abatacept Also Interacts With
- Adalimumab moderate
- Certolizumab moderate
- Etanercept moderate
- Infliximab moderate
Golimumab Also Interacts With
- Warfarin minor
- Methotrexate minor
- Cyclosporine minor
- Theophylline minor
Frequently Asked Questions
What SPL severity band is on file for Abatacept + Golimumab?
Compiled FDA labeling labels this pair moderate. That is a source-record field, not an individual medication-combination decision.
How many labeled pairs sit in each drug's moderate band?
Abatacept and Golimumab tie at 5 labeled pairs each. moderate-band counts: Abatacept 5 alongside Adalimumab, Certolizumab, Etanercept, Infliximab; Golimumab 1.
What mechanism field is on file for Abatacept and Golimumab?
Both of these drugs weaken the immune system to treat inflammation. Using them together makes it much harder for your body to fight off serious infections without providing extra help for your condition.
Abatacept and Golimumab · moderate-band peers
SPL source-record counts only. This page's band is moderate · classes on file: Abatacept (T-Cell Co-Stimulation Modulator); Golimumab (TNF-Alpha Inhibitor (Biologic)).
0 major · 5 moderate · 0 minor · 5 total
- Other moderate peers for Abatacept
- Adalimumab
- Certolizumab
- Etanercept
- Infliximab
0 major · 1 moderate · 4 minor · 5 total
Golimumab has no other moderate-band peer in this dataset besides Abatacept.
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.