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triazolam Side Effects

Also known as: Halcion

Analysis of 8,521 adverse event reports submitted to the FDA from 2004 to 2025.

Total Reports

8,521

Death-Related

1,218

14.3% of reports

Hospitalizations

3,668

43.0% of reports

Top Indication

Product Used For Unknown Indication

Most Reported Adverse Reactions

DRUG ABUSE
519
DRUG INEFFECTIVE
450
SOPOR
402
NAUSEA
352
OVERDOSE
350
FALL
315
INSOMNIA
303
PYREXIA
302
SUICIDE ATTEMPT
302
DIARRHOEA
290
DIZZINESS
282
SOMNOLENCE
280
MALAISE
267
HEADACHE
262
LOSS OF CONSCIOUSNESS
260
INTENTIONAL OVERDOSE
255
FATIGUE
251
DRUG INTERACTION
250
TOXICITY TO VARIOUS AGENTS
238
VOMITING
237

Who Reports Side Effects

Gender Distribution

Female 4,618 (58%)
Male 3,312 (42%)
Unknown 30

Age Distribution

0-17 167 (3%)
18-44 1,184 (19%)
45-64 1,850 (29%)
65-74 1,371 (22%)
75+ 1,727 (27%)

Reporting Trend by Year

2004 2025

Reactions in Death Reports

Top reactions reported in 1,218 reports where death was an outcome. These are voluntarily reported and do not establish causation.

Reaction Reports
COMPLETED SUICIDE 222
DEATH 200
TOXICITY TO VARIOUS AGENTS 135
PNEUMONIA 80
OVERDOSE 76
CARDIO-RESPIRATORY ARREST 46
DIARRHOEA 46
INTERSTITIAL LUNG DISEASE 46
RESPIRATORY FAILURE 46
CARDIAC ARREST 42
CARDIAC FAILURE 41
NAUSEA 40
PYREXIA 40
VOMITING 40
DRUG ABUSE 37
DEPRESSED LEVEL OF CONSCIOUSNESS 34
DRUG INTERACTION 34
MALIGNANT NEOPLASM PROGRESSION 33
FALL 32
DYSPNOEA 31

Reactions in Hospitalization Reports

Top reactions in 3,668 reports where hospitalization was an outcome.

Reaction Reports
DRUG ABUSE 321
SOPOR 286
PYREXIA 197
FALL 194
OVERDOSE 193
SUICIDE ATTEMPT 182
INTENTIONAL OVERDOSE 167
PNEUMONIA 162
NAUSEA 153
DYSPNOEA 146
LOSS OF CONSCIOUSNESS 144
DRUG INTERACTION 140
VOMITING 138
DIARRHOEA 134
MALAISE 119
INTENTIONAL SELF-INJURY 116
SOMNOLENCE 115
DEHYDRATION 114
DIZZINESS 114
ASTHENIA 107

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What the FAERS Data Reveals About triazolam Side Effects

The FDA Adverse Event Reporting System (FAERS) contains 8,521 voluntary reports linked to triazolam and its brand equivalents (Halcion), spanning 2004 through 2025. Of those, 1,218 (14.3%) listed death as an outcome and 3,668 (43.0%) involved hospitalization. The most common indication reported alongside adverse events was Product Used For Unknown Indication.

Demographic breakdowns help contextualize who is being exposed to the drug. Of reports with known sex, 58% were female and 42% male; age distribution skews toward 45-64, with 1,850 reports in that bracket. The single most reported reaction is drug abuse with 519 submissions, followed by drug ineffective and sopor.

FAERS is a signal-detection tool, not a scorecard. Reports are voluntary, and a single case may list multiple suspect drugs, so numbers above should not be read as incidence rates or per-patient risk. Widely prescribed drugs naturally accumulate more reports than niche therapies even when individual risk is low. These aggregates are useful for spotting patterns that merit further pharmacovigilance, not for choosing between medications. This page is for educational reference only and is not medical advice — speak with a licensed clinician about any side-effect concerns.