MID-VOLUME · HOSP-HEAVY
daptomycin Side Effects
daptomycin (also sold as Cubicin) sits MID-VOLUME #338 of 524 by FAERS report count. Lead signal: HOSP-HEAVY - 57.2% mention hospitalization (4,822 reports). Demographics and serious-outcome tables follow.
Data updated 2026-05-15
- 8,426
- FAERS reports
FDA Adverse Event Reporting System extract for daptomycin. Stamp set WATCHLIST · DEATH-HEAVY · HOSP-HEAVY. How figures are compiled.
daptomycin: 57.2% mention hospitalization (4,822 reports). Death stamp DEATH-HEAVY; volume band MID-VOLUME #338 of 524 by FAERS report count.
Mid-book FAERS page for daptomycin (Cubicin) (8,426 reports). Signature HOSP-HEAVY. Dominant age band on file: 45-64. Educational reference only.
Counts from the openFDA FAERS extract (2004–2025). Stamps WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ACUTE KIDNEY INJURY leads 527 of 8,426 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (2,369 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (1,184 reports, 14.1%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 160 |
| MULTIPLE ORGAN DYSFUNCTION SYNDROME | 127 |
| SEPSIS | 114 |
| SEPTIC SHOCK | 105 |
| ACUTE KIDNEY INJURY | 68 |
| PNEUMONIA | 63 |
| THROMBOCYTOPENIA | 57 |
| EOSINOPHILIC PNEUMONIA | 48 |
| NEUTROPENIA | 44 |
| RESPIRATORY FAILURE | 44 |
| ENTEROCOCCAL INFECTION | 42 |
| DYSPNOEA | 41 |
| CARDIAC ARREST | 40 |
| STAPHYLOCOCCAL INFECTION | 37 |
| TREATMENT FAILURE | 37 |
| HYPOTENSION | 36 |
| PYREXIA | 36 |
| CONDITION AGGRAVATED | 33 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (4,822, 57.2% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| ACUTE KIDNEY INJURY | 395 |
| PYREXIA | 303 |
| EOSINOPHILIC PNEUMONIA | 284 |
| EOSINOPHILIA | 252 |
| RHABDOMYOLYSIS | 244 |
| DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS | 215 |
| THROMBOCYTOPENIA | 179 |
| INTERSTITIAL LUNG DISEASE | 172 |
| AGRANULOCYTOSIS | 155 |
| NEUTROPENIA | 153 |
| BLOOD CREATINE PHOSPHOKINASE INCREASED | 149 |
| RASH | 143 |
| SEPSIS | 140 |
| DRUG INTERACTION | 135 |
| HEPATIC CYTOLYSIS | 135 |
| PNEUMONIA | 131 |
| DYSPNOEA | 124 |
| PNEUMONITIS | 124 |
How to read daptomycin FAERS figures (WATCHLIST · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 8,426 voluntary reports linked to daptomycin (Cubicin), 2004-2025. Death is listed on 1,184 (14.1%). Hospitalization appears on 4,822 (57.2%). Top co-reported indication: Product Used For Unknown Indication.
Mid-volume extract - treat DEATH-HEAVY · HOSP-HEAVY as signal-detection rates next to 57.2% mention hospitalization (4,822 reports).
Read with daptomycin
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 8,423 FAERS cases (Δ 3 lighter vs daptomycin); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 8,408 FAERS cases (Δ 18 lighter vs daptomycin); DEATH-MARKED · HOSP-MID · FEMALE-LED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 8,461 FAERS cases (Δ 35 heavier vs daptomycin); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 8,521 FAERS cases (Δ 95 heavier vs daptomycin); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 48.1 pp vs daptomycin's DEATH-HEAVY): CASELOAD · HOSP-MID.
daptomycin stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload WATCHLIST and the label guide.