HIGH-VOLUME · HOSP-HEAVY
tramadol Side Effects
tramadol (also sold as Ultram, ConZip) is HIGH-VOLUME in this FAERS book #171 of 524 by FAERS report count. Signature opener: HOSP-HEAVY - 31.0% mention hospitalization (11,220 reports).
Data updated 2026-05-15
- 36,174
- FAERS reports
FAERS voluntary reports, 1997 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
tramadol: 31.0% mention hospitalization (11,220 reports). Death stamp DEATH-HEAVY; volume band HIGH-VOLUME #171 of 524 by FAERS report count.
High-report extract for tramadol (Ultram): 36,174 FAERS rows (1997-2025). Top named reactions: DEPENDENCE, OVERDOSE, VOMITING. Outcome stamps DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (1997–2025). Stamps CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
DEPENDENCE leads 7,820 of 36,174 reports
Who reports · age peak 18-44 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 18-44 (5,980 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (6,870 reports, 19.0%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 1,793 |
| VOMITING | 1,219 |
| TYPE 2 DIABETES MELLITUS | 1,048 |
| FATIGUE | 1,044 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 1,042 |
| SYSTEMIC LUPUS ERYTHEMATOSUS | 1,040 |
| PSORIATIC ARTHROPATHY | 1,016 |
| WOUND | 1,016 |
| INFUSION RELATED REACTION | 1,015 |
| SYNOVITIS | 1,015 |
| OVERDOSE | 1,009 |
| RASH | 996 |
| RHEUMATOID ARTHRITIS | 989 |
| HYPOAESTHESIA | 986 |
| JOINT SWELLING | 971 |
| FOLLICULITIS | 962 |
| ARTHRALGIA | 958 |
| IRRITABLE BOWEL SYNDROME | 957 |
| DIARRHOEA | 955 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (11,220, 31.0% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| VOMITING | 1,522 |
| NAUSEA | 1,279 |
| HYPERTENSION | 1,268 |
| FATIGUE | 1,220 |
| CONFUSIONAL STATE | 1,186 |
| PAIN | 1,160 |
| HEADACHE | 1,158 |
| RASH | 1,113 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 1,064 |
| DIARRHOEA | 1,047 |
| DIZZINESS | 1,042 |
| ARTHRALGIA | 1,017 |
| RHEUMATOID ARTHRITIS | 1,016 |
| INFUSION RELATED REACTION | 1,001 |
| HYPOAESTHESIA | 994 |
| DYSPNOEA | 993 |
| SYNOVITIS | 977 |
| SYSTEMIC LUPUS ERYTHEMATOSUS | 973 |
How to read tramadol FAERS figures (CASELOAD · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 36,174 voluntary reports linked to tramadol (Ultram, ConZip), 1997-2025. Death is listed on 6,870 (19.0%). Hospitalization appears on 11,220 (31.0%). Top co-reported indication: Product Used For Unknown Indication.
CASELOAD books overweight common drugs and loud reporting cultures; HOSP-HEAVY is the page opener, not a per-patient risk.
Read with tramadol
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 35,897 FAERS cases (Δ 277 lighter vs tramadol); DEATH-MARKED · HOSP-LIGHT · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 36,885 FAERS cases (Δ 711 heavier vs tramadol); DEATH-MARKED · HOSP-MID · FEMALE-LED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 36,917 FAERS cases (Δ 743 heavier vs tramadol); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 36,931 FAERS cases (Δ 757 heavier vs tramadol); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 43.1 pp vs tramadol's DEATH-HEAVY): CASELOAD · HOSP-MID.
tramadol stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload CASELOAD and the label guide.