MID-VOLUME · HOSP-HEAVY
phytonadione Side Effects
phytonadione (also sold as Vitamin K1, Mephyton) sits MID-VOLUME #342 of 524 by FAERS report count. Lead signal: HOSP-HEAVY - 46.5% mention hospitalization (3,758 reports). Demographics and serious-outcome tables follow.
Data updated 2026-05-15
- 8,078
- FAERS reports
FDA Adverse Event Reporting System extract for phytonadione. Stamp set WATCHLIST · DEATH-HEAVY · HOSP-HEAVY. How figures are compiled.
phytonadione: 46.5% mention hospitalization (3,758 reports). Death stamp DEATH-HEAVY; volume band MID-VOLUME #342 of 524 by FAERS report count.
Mid-book FAERS page for phytonadione (Vitamin K1) (8,078 reports). Signature HOSP-HEAVY. Dominant age band on file: 45-64. Educational reference only.
Counts from the openFDA FAERS extract (1999–2025). Stamps WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
NAUSEA leads 630 of 8,078 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (1,708 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (1,508 reports, 18.7%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| SEPSIS | 344 |
| MULTIPLE ORGAN DYSFUNCTION SYNDROME | 304 |
| DEATH | 279 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 279 |
| VOMITING | 278 |
| ASCITES | 274 |
| NAUSEA | 269 |
| ABDOMINAL DISTENSION | 265 |
| ABDOMINAL PAIN | 265 |
| HYPONATRAEMIA | 256 |
| STRESS | 240 |
| APPENDICITIS | 238 |
| APPENDICOLITH | 237 |
| CARDIOGENIC SHOCK | 235 |
| CONSTIPATION | 233 |
| VENTRICULAR FIBRILLATION | 219 |
| CONDITION AGGRAVATED | 205 |
| ANAEMIA | 183 |
| SOMNOLENCE | 179 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (3,758, 46.5% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| DYSPNOEA | 323 |
| VOMITING | 315 |
| NAUSEA | 311 |
| SEPSIS | 284 |
| ANAEMIA | 281 |
| PNEUMONIA | 259 |
| PYREXIA | 250 |
| ABDOMINAL PAIN | 246 |
| CONDITION AGGRAVATED | 234 |
| DIARRHOEA | 220 |
| FATIGUE | 214 |
| ASCITES | 206 |
| CONSTIPATION | 190 |
| ABDOMINAL DISTENSION | 188 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 180 |
| MULTIPLE ORGAN DYSFUNCTION SYNDROME | 180 |
| PULMONARY EMBOLISM | 179 |
| HYPONATRAEMIA | 174 |
How to read phytonadione FAERS figures (WATCHLIST · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 8,078 voluntary reports linked to phytonadione (Vitamin K1, Mephyton), 1999-2025. Death is listed on 1,508 (18.7%). Hospitalization appears on 3,758 (46.5%). Top co-reported indication: Product Used For Unknown Indication.
Mid-volume extract - treat DEATH-HEAVY · HOSP-HEAVY as signal-detection rates next to 46.5% mention hospitalization (3,758 reports).
Read with phytonadione
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 8,141 FAERS cases (Δ 63 heavier vs phytonadione); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 7,980 FAERS cases (Δ 98 lighter vs phytonadione); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 7,881 FAERS cases (Δ 197 lighter vs phytonadione); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 7,819 FAERS cases (Δ 259 lighter vs phytonadione); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 43.4 pp vs phytonadione's DEATH-HEAVY): CASELOAD · HOSP-MID.
phytonadione stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload WATCHLIST and the label guide.